4,4,4-Trifluoro-1-(4-trifluoromethylphenyl)-1,3-butanedione → HCID 11441169, Verbindung

Beteiligte Stoffe

Reaktionsschritte

Reaction of 1-(4-trifluoromethyl-phenyl)-4,4,4-trifluoro-butane-1,3-dione (142 mg, 0.5 mmol), prepared from commercially available 4-trifluoromethyl-acetophenone according to general procedure A, and 3-amino-4-(4-pyridinyl)-pyrazole [CAS No. 216661-87-9; prepared from 4-cyanomethyl-pyridine as described in Bioorg. Med. Chem. Lett. 12 (2002) 3537-3541] (80 mg, 0.5 mmol) according to general procedure B yielded the title compound as a yellow solid (93 mg, 46%). MS (ISP) 409.2 [(M+H)+]; mp 261° C.

Herkunft & Nachweise