HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → {4-[2-(4-Fluorophenyl)ethyl]piperazin-1-yl}isoquinolin-1-ylmethanone, hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | {4-[2-(4-Fluorophenyl)ethyl]piperazin-1-yl}isoquinolin-1-ylmethanone | HCID 9885359 | — |
| Lösungsmittel | Acetone | HCID 180 | — |
| Lösungsmittel | Diethyl Ether | HCID 3283 | — |
| Produkt | {4-[2-(4-Fluorophenyl)ethyl]piperazin-1-yl}isoquinolin-1-ylmethanone, hydrochloride | HCID 131726767 | — |
Reaktionsschritte
For salt formation, 1N hydrochloric acid is added to a solution of {4-[2-(4-fluorophenyl)ethyl]piperazin-1-yl}isoquinolin-1-ylmethanone in 60 ml of acetone and 50 ml of ether until crystals form. When crystallisation is complete, the mother liquor is filtered off, and the precipitate is washed with ether and dried, giving {4-[2-(4-fluorophenyl)ethyl]piperazin-1-yl}isoquinolin-1-ylmethanone, hydrochloride, m.p. 238-240°.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07329749B2 |
| Quelldatensatz | uspto-grants-2008_02 |
| ORD ID | ord-d0a23f68871b41f4a282286bf96a4ab9 |
| Quellennotiz | uspto-grants-2008_02 |