HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,3-Difluorobenzoyl chloride → 5-Bromo-1'-{[6-chloro-1-(2,3-difluorobenzoyl)-1H-indol-3-yl]carbonyl}-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,3-Difluorobenzoyl chloride | HCID 519549 | — |
| Edukt | 5-bromo-1'-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 59657619 | — |
| Produkt | 5-Bromo-1'-{[6-chloro-1-(2,3-difluorobenzoyl)-1H-indol-3-yl]carbonyl}-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 59657663 | — |
Reaktionsschritte
Following the general procedure VII as describeed above, the acylation of 5-bromo-1′-[(6-chloro-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one with commercially available 2,3-difluorobenzoyl chloride gave the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07332501B2 |
| Quelldatensatz | uspto-grants-2008_02 |
| ORD ID | ord-31aad50b250b4b2d8d22b69fe4051131 |
| Quellennotiz | uspto-grants-2008_02 |