(3R)-3-methyl-1-(1H,3H-naphtho[1,8-cd]pyran-6-yl)piperazine → (3R)-3-methyl-1-(1H,3H-naphtho[1,8-cd]thiopyran-6-yl)piperazine

HRID 2056741

Reaktionsgleichung

Reaktionsgleichung von HRID 2056741
[CH3:1][C@H:2]1[NH:7][CH2:6][CH2:5][N:4]([C:8]2[CH:9]=[CH:10][C:11]3[CH2:12]O[CH2:14][C:15]4[C:16]=3[C:17]=2[CH:18]=[CH:19][CH:20]=4)[CH2:3]1.BrC1C=CC2C[S:27]CC3C=2C=1C=CC=3>>[CH3:1][C@H:2]1[NH:7][CH2:6][CH2:5][N:4]([C:8]2[CH:9]=[CH:10][C:11]3[CH2:12][S:27][CH2:14][C:15]4[C:16]=3[C:17]=2[CH:18]=[CH:19][CH:20]=4)[CH2:3]1

Komponenten

3

Edukt 2

HCID 69306502(3R)-3-methyl-1-(1H,3H-naphtho[1,8-cd]pyran-6-yl)piperazineHCID 693077926-bromo-1H,3H-naphtho[1,8-cd]thiopyran

Produkt 1

HCID 69307284(3R)-3-methyl-1-(1H,3H-naphtho[1,8-cd]thiopyran-6-yl)piperazine

Versuchsvorschrift

The procedure used for the synthesis of (3R)-3-methyl-1-(1H,3H-naphtho[1,8-cd]pyran-6-yl)piperazine (Example 5b)) was followed, using 6-bromo-1H,3H-naphtho[1,8-cd]thiopyran as starting material and making non-critical variations, to obtain the title compound (3R)-3-methyl-1-(1H,3H-naphtho[1,8-cd]thiopyran-6-yl)piperazine as brown solid.

Quellen und Nachweise

ORD-Eintrag
ord-2a669c62074d4c03baaea38a701ea01b
Quelldatensatz
uspto-grants-2008_02
Patentnummer
US07335660B2

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