1-(2-Hydroxyethyl)-3,4-dihydro-1H-2-benzopyran-6-carbonitrile → 2-(6-Cyano-3,4-dihydro-1H-2-benzopyran-1-yl)ethyl methanesulfonate
Reaktionsgleichung
OCCC1C2C=CC(C#N)=CC=2CCO1.[CH3:16][S:17]([O:20][CH2:21][CH2:22][C@H:23]1[C:28]2[CH:29]=[CH:30][C:31]([C:33]([NH2:35])=O)=[CH:32][C:27]=2[CH2:26][CH2:25][O:24]1)(=[O:19])=[O:18]>>[CH3:16][S:17]([O:20][CH2:21][CH2:22][CH:23]1[C:28]2[CH:29]=[CH:30][C:31]([C:33]#[N:35])=[CH:32][C:27]=2[CH2:26][CH2:25][O:24]1)(=[O:18])=[O:19]Komponenten
3
Versuchsvorschrift
Prepared from 1-(2-hydroxyethyl)-3,4-dihydro-1H-2-benzopyran-6-carbonitrile, as described for the preparation of 2-[(1S)-6-(aminocarbonyl)-3,4-dihydro-1H-2-benzopyran-1-yl]ethyl methanesulfonate.
Quellen und Nachweise
- ORD-Eintrag
- ord-0cc39b79a40e4d77b98a05a0b6ccc067
- Quelldatensatz
- uspto-grants-2008_02