HCID 22337641, Verbindung → HCID 22337569, Verbindung
Reaktionsgleichung
[C:1]([O:4][C:5]1[N:6]=[CH:7][C:8]2[C:13]([CH:14]=1)=[C:12]([N+:15]([O-])=O)[CH:11]=[CH:10][CH:9]=2)(=[O:3])[CH3:2].[H][H]>O1CCOCC1.[Ni]>[C:1]([O:4][C:5]1[N:6]=[CH:7][C:8]2[C:13]([CH:14]=1)=[C:12]([NH2:15])[CH:11]=[CH:10][CH:9]=2)(=[O:3])[CH3:2]Komponenten
5
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
5-Nitro-3-isoquinolinyl acetate (50 mg, 0.21 mmol) in 1,4-dioxane (20 mL) was treated with Raney-nickel powder (85 mg) and exposed to a hydrogen atmosphere via a balloon for 16 hours. The mixture was filtered through a plug of Celite and the filtrate was concentrated under reduced pressure to provide the title compound which was used without further purification.
Aufarbeitung
- filtrationThe mixture was filtered through a plug of Celite
- concentrationthe filtrate was concentrated under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-3865fc75690b424194ca0c7e00479ff1
- Quelldatensatz
- uspto-grants-2008_02
- Patentnummer
- US07335678B2
Notizen zur Reaktion
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