2-Amino-2-phenylacetonitrile → 1-(4-Amino-2-methyl-5-phenyl-1H-pyrrol-3-yl)-1-propanone
Reaktionsgleichung
[NH2:1][CH:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[C:3]#[N:4].[CH3:11][C:12](=O)[CH2:13][C:14](=[O:17])[CH2:15][CH3:16]>CO>[NH2:4][C:3]1[C:13]([C:14](=[O:17])[CH2:15][CH3:16])=[C:12]([CH3:11])[NH:1][C:2]=1[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Starting from 2-amino-2-phenylacetonitrile and hexane-2,4-dione, the open-chain intermediate compound is obtained, b.p. 160° C./0.3 mm Hg. The title compound is obtained in an overall yield of 53%, m.p. 166°-168° C. (from methanol).
Aufarbeitung
- customthe open-chain intermediate compound is obtained
Quellen und Nachweise
- ORD-Eintrag
- ord-153d6e9659764b0fbb5be8ed03b94e9d
- Quelldatensatz
- uspto-grants-1980_07
- Patentnummer
- US04211708
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