Sodium Hydroxide → Sodium 2-[4-(4-chloroanilinomethyl)-2-hydroxyphenoxy]-2-methylpropionate
Reaktionsgleichung
[CH3:1][C:2]1([CH3:22])[C:7](=[O:8])[O:6][C:5]2[CH:9]=[C:10]([CH2:13][NH:14][C:15]3[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=3)[CH:11]=[CH:12][C:4]=2[O:3]1.[OH-:23].[Na+:24]>C(O)C>[Cl:21][C:18]1[CH:19]=[CH:20][C:15]([NH:14][CH2:13][C:10]2[CH:11]=[CH:12][C:4]([O:3][C:2]([CH3:22])([CH3:1])[C:7]([O-:6])=[O:8])=[C:5]([OH:23])[CH:9]=2)=[CH:16][CH:17]=1.[Na+:24]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of 158.7 mg of 3,3-dimethyl-7-(4-chloroanilinomethyl)-1,4-benzodioxan-2-one in 10 ml of ethanol is added 5 ml of a 1/10 N sodium hydroxide aqueous solution and the mixture is warmed to give clear solution. The solution is concentrated and the precipitated crystals are collected by filtration, washed with water and ether, and dried to give 140 mg of sodium 2-[4-(4-chloroanilinomethyl)-2-hydroxyphenoxy]-2-methylpropionate, mp 121° to 125° C.