2-Amino-5-cyanopyridine → 3-[3-[tert-butyl(dimethyl)silyl]oxyazetidin-1-yl]-N-(5-cyano-2-pyridinyl)-2-[1-(2,6-dichlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxypropanamide

Reaktionsgleichung

[C:10]([CH3:11])([CH3:12])([CH3:13])[Si:14]([O:15][CH:16]1[CH2:17][N:18]([CH2:20][CH:21]([C:22](=[O:23])[O:24][CH3:25])[O:26][c:27]2[c:28]3[c:29]([n:30][cH:31][n:32]2)[n:33](-[c:36]2[c:37]([Cl:43])[cH:38][cH:39][cH:40][c:41]2[Cl:42])[n:34][cH:35]3)[CH2:19]1)([CH3:44])[CH3:45].[NH2:1][c:2]1[n:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1>>[NH:1]([c:2]1[n:3][cH:4][c:5]([C:6]#[N:7])[cH:8][cH:9]1)[C:22]([CH:21]([CH2:20][N:18]1[CH2:17][CH:16]([O:15][Si:14]([C:10]([CH3:11])([CH3:12])[CH3:13])([CH3:44])[CH3:45])[CH2:19]1)[O:26][c:27]1[c:28]2[c:29]([n:30][cH:31][n:32]1)[n:33](-[c:36]1[c:37]([Cl:43])[cH:38][cH:39][cH:40][c:41]1[Cl:42])[n:34][cH:35]2)=[O:23]