Dichloromethane → HCID 12962282, Verbindung

HRID 2059108Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2059108
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]2[NH:14][CH2:13][CH2:12][O:11]2)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].C(Cl)Cl.[Cl:18][CH:19]([Cl:23])[C:20](Cl)=[O:21]>C(N(CC)CC)C>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]2[N:14]([C:20](=[O:21])[CH:19]([Cl:23])[Cl:18])[CH2:13][CH2:12][O:11]2)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2]

Komponenten

5

Edukt 3

HCID 6344DichloromethaneHCID 6593Dichloroacetyl chlorideHCID 2417432-(3-Nitrophenyl)-1,3-oxazolidine

Produkt 1

HCID 12962282HCID 12962282, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8471TriethylamineLösungsmittel

Versuchsvorschrift

Five and eight tenths (5.8) grams of 2-m-nitrophenyl oxazolidine was dissolved in 50 ml. methylene chloride containing 3.5 g. of triethylamine. Dichloroacetyl chloride 4.4 g. was added dropwise with stirring to the reaction flask and cooled in a water bath at room temperature. When addition was complete, the mixture was stirred at room temperature for about 30 minutes, washed with water, separated and dried over anhydrous magnesium sulfate. The solvent was stripped off under vacuum. There was obtained a yield of 8.6 g. of the title compound, ND30 =1.5590.

Aufarbeitung

  1. additionwas added dropwise
  2. additionWhen addition
  3. stirringthe mixture was stirred at room temperature for about 30 minutes
  4. washwashed with water
  5. customseparated
  6. dry with materialdried over anhydrous magnesium sulfate
  7. customThere was obtained a yield of 8.6 g

Quellen und Nachweise

ORD-Eintrag
ord-54930fd970984dabb4766d6ef47a8a05
Quelldatensatz
uspto-grants-1982_03
Patentnummer
US04322240

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