HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,6-Dimethoxybenzoyl chloride → 2,6-Dimethoxy-N-(4-(4-(trifluoromethyl)phenyl)-5-isoxazolyl)benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,6-Dimethoxybenzoyl chloride | HCID 74810 | — |
| Edukt | 4-(4-(Trifluoromethyl)phenyl)-5-aminoisoxazole | HCID 20546740 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | 2,6-Dimethoxy-N-(4-(4-(trifluoromethyl)phenyl)-5-isoxazolyl)benzamide | HCID 13035564 | — |
Reaktionsschritte
4-(4-(Trifluoromethyl)phenyl)-5-aminoisoxazole (1.0 g) and 2,6-dimethoxybenzoylchloride (2 g) were refluxed in 100 ml. toluene for 3 hours. The reaction mixture was cooled and the final product was then collected and recrystallized from ethanol, m.p. 199°-201° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04322429 |
| Quelldatensatz | uspto-grants-1982_03 |
| ORD ID | ord-680c61f813ff4726bed668b4b9331c3a |
| Quellennotiz | uspto-grants-1982_03 |