Furfural → 5-Furan-2-yl-3-hydroxy-1-(3-imidazol-1-yl-propyl)-4-pentyl-1,5-dihydro-pyrrol-2-one
Reaktionsgleichung
[N:1]1([CH2:6][CH2:7][CH2:8][NH2:9])[CH:5]=[CH:4][N:3]=[CH:2]1.[O:10]1[CH:14]=[CH:13][CH:12]=[C:11]1[CH:15]=O.C([O:19][C:20](=O)[C:21](=[O:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])C>C(O)C>[O:10]1[CH:14]=[CH:13][CH:12]=[C:11]1[CH:15]1[N:9]([CH2:8][CH2:7][CH2:6][N:1]2[CH:5]=[CH:4][N:3]=[CH:2]2)[C:20](=[O:19])[C:21]([OH:28])=[C:22]1[CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 50 °C
Versuchsvorschrift
3-Imidazol-1-yl-propylamine (1 mmol) and Furan-2-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 2-Oxo-octanoic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.
Aufarbeitung
- customAfter evaporation of the solvent the residue
- customwas purified with chromatographic methods
Quellen und Nachweise
- ORD-Eintrag
- ord-1744b439609d4f2e86b9c88172d0c475
- Quelldatensatz
- uspto-grants-2012_10
- Patentnummer
- US08278345B2
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