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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2064854Erstellt: 27. Oktober 2026

6-fluoro-4H-1,3-benzodioxine-8-carboxylic acid → 6-fluoro-4H-benzo[1,3]dioxine-8-carboxylic acid {(1S,3S,5S)-2-[5-(3-fluoro-phenyl)-2-methyl-thiazole-4-carbonyl]-2-aza-bicyclo[3.1.0]hex-3-ylmethyl}-amide

https://huagongshe.com/reaction/2064854

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt6-fluoro-4H-1,3-benzodioxine-8-carboxylic acidHCID 2779901—
Edukt[(1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl]-[5-(3-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanoneHCID 67081101—
Produkt6-fluoro-4H-benzo[1,3]dioxine-8-carboxylic acid {(1S,3S,5S)-2-[5-(3-fluoro-phenyl)-2-methyl-thiazole-4-carbonyl]-2-aza-bicyclo[3.1.0]hex-3-ylmethyl}-amideHCID 67081217—

Reaktionsschritte

prepared by reaction of [(1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl]-[5-(3-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone with 6-fluoro-4H-benzo[1,3]dioxine-8-carboxylic acid. LC-MS (basic): tR=0.89 min; [M+H]+=512.1.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08288435B2
Quelldatensatzuspto-grants-2012_10
ORD IDord-b02da52f37a44750b6921a3b59c11101
Quellennotizuspto-grants-2012_10