HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Methyl-5-(trifluoromethyl)pyrazole-4-carboxylic Acid → 1-methyl-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid {(1S,3S,5S)-2-[5-(3-fluoro-phenyl)-2-methyl-thiazole-4-carbonyl]-2-aza-bicyclo[3.1.0]hex-3-ylmethyl}-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Methyl-5-(trifluoromethyl)pyrazole-4-carboxylic Acid | HCID 2807771 | — |
| Edukt | [(1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl]-[5-(3-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone | HCID 67081101 | — |
| Produkt | 1-methyl-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid {(1S,3S,5S)-2-[5-(3-fluoro-phenyl)-2-methyl-thiazole-4-carbonyl]-2-aza-bicyclo[3.1.0]hex-3-ylmethyl}-amide | HCID 67081073 | — |
Reaktionsschritte
prepared by reaction of [(1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl]-[5-(3-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone with 1-methyl-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid. LC-MS (basic): tR=0.85 min; [M+H]+=508.1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08288435B2 |
| Quelldatensatz | uspto-grants-2012_10 |
| ORD ID | ord-bfa01c5e9029459c9b2bd6950205479f |
| Quellennotiz | uspto-grants-2012_10 |