HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Quinolinecarboxylic acid → quinoline-4-carboxylic acid {(1S,3S,5S)-2-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-2-aza-bicyclo[3.1.0]hex-3-ylmethyl}-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Quinolinecarboxylic acid | HCID 10243 | — |
| Edukt | [2-amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl)-methanone | HCID 86653658 | — |
| Produkt | quinoline-4-carboxylic acid {(1S,3S,5S)-2-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-2-aza-bicyclo[3.1.0]hex-3-ylmethyl}-amide | HCID 86653664 | — |
Reaktionsschritte
prepared by reaction of [2-amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl)-methanone with quinoline-4-carboxylic acid. LC-MS (basic): tR=0.77 min; [M+H]+=488.1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08288435B2 |
| Quelldatensatz | uspto-grants-2012_10 |
| ORD ID | ord-6927fc4cf02b4600b986a3c5c8eacb9a |
| Quellennotiz | uspto-grants-2012_10 |