HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
L-(-)-Tryptophanol → 6-Chloro-2-[(S)-1-hydroxymethyl-2-(1H-indol-3-yl)-ethylamino]-quinoline-3-carboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | L-(-)-Tryptophanol | HCID 6951149 | — |
| Edukt | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Produkt | 6-Chloro-2-[(S)-1-hydroxymethyl-2-(1H-indol-3-yl)-ethylamino]-quinoline-3-carboxylic acid | HCID 45257059 | 73% |
Reaktionsschritte
In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with L-tryptophanol to provide the title compound in 73% yield as yellow needles (recrystallization from EtOH).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08288549B2 |
| Quelldatensatz | uspto-grants-2012_10 |
| ORD ID | ord-680c388c44044c8ea031615f829d84c2 |
| Quellennotiz | uspto-grants-2012_10 |