4-Carboxyphenylalanine → HCID 45255160, Verbindung

HRID 2065636Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2065636
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[C:16]([C:19]1[CH:30]=[CH:29][C:22]([CH2:23][CH:24]([C:26]([OH:28])=[O:27])[NH2:25])=[CH:21][CH:20]=1)([OH:18])=[O:17]>>[C:26]([CH:24]([NH:25][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)[CH2:23][C:22]1[CH:29]=[CH:30][C:19]([C:16]([OH:18])=[O:17])=[CH:20][CH:21]=1)([OH:28])=[O:27]

Komponenten

3

Edukt 2

HCID 2652734-CarboxyphenylalanineHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

Produkt 1

HCID 45255160HCID 45255160, Verbindung

Versuchsvorschrift

In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 4-carboxy-DL-phenylalanine and crude product is separated by flash chromatography on SiO2 to provide the title compound in good yield.

Aufarbeitung

  1. customis separated by flash chromatography on SiO2

Quellen und Nachweise

ORD-Eintrag
ord-a1b5ee2daaf14c548010279edd8b3ec4
Quelldatensatz
uspto-grants-2012_10
Patentnummer
US08288549B2

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