HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethyl 6-bromohexanoate → Ethyl 6-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-oxo-2H-chromen-8-yloxy)hexanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethyl 6-bromohexanoate | HCID 117544 | — |
| Edukt | 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one | HCID 24849570 | — |
| Produkt | Ethyl 6-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-oxo-2H-chromen-8-yloxy)hexanoate | HCID 24849664 | — |
Reaktionsschritte
The title compound was prepared from ethyl 6-bromohexanoate and 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one (Example 29) following the procedure outlined in Example 25. 1H NMR (400 MHz, DMSO-d6): δ 9.51 (s, 1H), 8.81 (s, 2H), 7.94 (d, 1H), 7.20 (d, 1H), 4.63 (s, 1H), 4.02 (q, 2H), 3.97 (t, 2H), 3.91 (s, 3H), 2.39 (t, 2H), 1.67 (m, 2H), 1.57 (m, 2H), 1.46 (m, 2H), 1.15 (t, 3H); MS (ESI): 494.9.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07745646B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-971be59233fa44729fc045080b5484f5 |
| Quellennotiz | uspto-grants-2010_06 |