3-Butyn-1-OL → [2-Chloro-4-(2,4-difluoro-phenylamino)-phenyl]-{5-[4-(2-hydroxy-ethyl)-[1,2,3]triazol-1-yl]-2-methyl-phenyl}-methanone

Reaktionsgleichung

C(OC(=O)CN1C=C([C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[C:13]([C:18](=[O:35])[C:19]3[CH:24]=[CH:23][C:22]([NH:25][C:26]4[CH:31]=[CH:30][C:29]([F:32])=[CH:28][C:27]=4[F:33])=[CH:21][C:20]=3[Cl:34])[CH:12]=2)N=N1)C.[N:37]([C:40]1C=CC(C)=[C:44]([C:46](C2C=CC(NC3C=CC(F)=CC=3F)=CC=2Cl)=[O:47])[CH:45]=1)=[N+:38]=[N-:39].C(O)CC#C>>[Cl:34][C:20]1[CH:21]=[C:22]([NH:25][C:26]2[CH:31]=[CH:30][C:29]([F:32])=[CH:28][C:27]=2[F:33])[CH:23]=[CH:24][C:19]=1[C:18]([C:13]1[CH:12]=[C:11]([N:37]2[CH:40]=[C:45]([CH2:44][CH2:46][OH:47])[N:39]=[N:38]2)[CH:16]=[CH:15][C:14]=1[CH3:17])=[O:35]