HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
DL-2-Amino-1-hexanol → N-[6-(1-Hydroxymethyl-pentylamino)-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl]-methanesulfonamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | DL-2-Amino-1-hexanol | HCID 249006 | — |
| Edukt | N-(6-fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide | HCID 58964482 | — |
| Produkt | N-[6-(1-Hydroxymethyl-pentylamino)-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl]-methanesulfonamide | HCID 69338669 | 61% |
Reaktionsschritte
N-(6-Fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide (30 mg, 0.0943 mmol) is reacted with 2-amino-hexan-1-ol according to the GPA affording 24 mg (61%) of a purple powder. Rt=4.5 min.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08299085B2 |
| Quelldatensatz | uspto-grants-2012_10 |
| ORD ID | ord-e697243bebe7454a91642ccd98f06175 |
| Quellennotiz | uspto-grants-2012_10 |