N-(6-fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide → HCID 69347645, Verbindung
Reaktionsgleichung
F[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[NH:8][C:7](=[O:15])[N:6]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[C:5]2=[O:21].[CH3:22][O:23][CH2:24][C:25]1[N:26]=[CH:27][NH:28][CH:29]=1>>[CH3:22][O:23][CH2:24][C:25]1[N:26]=[CH:27][N:28]([C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][C:11]=2[N+:12]([O-:14])=[O:13])[NH:8][C:7](=[O:15])[N:6]([NH:16][S:17]([CH3:20])(=[O:19])=[O:18])[C:5]3=[O:21])[CH:29]=1Komponenten
3
Versuchsvorschrift
N-(6-Fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide (50 mg, 0.157 mmol) is reacted with 4-methoxymethyl-1H-imidazole according to the GPB affording 36 mg (44%) of a yellow powder. Rt=2.20 min.
Quellen und Nachweise
- ORD-Eintrag
- ord-62df7d2501944abe82a16fa4d6394fc7
- Quelldatensatz
- uspto-grants-2012_10
- DOI