(2Z)-3-(2-cyanophenyl)prop-2-enoic acid → 3-(2-Cyanophenyl)propanoic acid

Beteiligte Stoffe

Reaktionsschritte

A slurry of (Z)-3-(2-cyanophenyl)acrylic acid (Example 323a, 4.75 g) in ethanol (50 mL) was added to 5% Palladium (0.292 g) in ethanol (50 mL) and hydrogenated under 2.0 bar hydrogen pressure for 2 h. The reaction mixture was filtered and the filtrate evaporated to dryness to afford the sub title compound as a solid (4.36 g).

Herkunft & Nachweise