Tert-butyl benzofuran-2-ylmethylcarbamate → [3-(Propan-2-yl)-1,2-oxazol-5-yl]methanamine
Reaktionsgleichung
[N:1]([CH2:4][C:5]1[O:9][N:8]=[C:7]([CH:10]([CH3:12])[CH3:11])[CH:6]=1)=[N+]=[N-].O1C2C=CC=CC=2C=C1CNC(=O)OC(C)(C)C>>[CH:10]([C:7]1[CH:6]=[C:5]([CH2:4][NH2:1])[O:9][N:8]=1)([CH3:12])[CH3:11]Komponenten
3
Versuchsvorschrift
(3-isopropylisoxazol-5-yl)methanamine was synthesized from 5-(azidomethyl)-3-isopropylisoxazole following the general procedure as described herein including the protection-deprotection steps to improve the purity of the amine.
Quellen und Nachweise
- ORD-Eintrag
- ord-4be9d7cba96e4d2f9851eeb159db773e
- Quelldatensatz
- uspto-grants-2012_10
- Patentnummer
- US08299267B2
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