4-Isopropoxycarbonylamino-2-nitroaniline → 1,2-Diamino-4-isopropoxycarbonylaminobenzene

HRID 2071797Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2071797
[N+:1]([C:4]1[CH:10]=[C:9]([NH:11][C:12]([O:14][CH:15]([CH3:17])[CH3:16])=[O:13])[CH:8]=[CH:7][C:5]=1[NH2:6])([O-])=O.[H][H]>CO.[Pt]=O>[NH2:6][C:5]1[CH:7]=[CH:8][C:9]([NH:11][C:12]([O:14][CH:15]([CH3:16])[CH3:17])=[O:13])=[CH:10][C:4]=1[NH2:1]

Komponenten

5

Edukt 2

HCID 126780374-Isopropoxycarbonylamino-2-nitroanilineHCID 178418361HCID 178418361, Verbindung2×

Produkt 1

HCID 126780381,2-Diamino-4-isopropoxycarbonylaminobenzeneAusbeute 66,3 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

A mixture of a solution of 2-nitro-4-isopropoxycarbonylaminoaniline (17.9 g, 0.075 mole) in methanol (450 ml) and platinum oxide (1.0 g) was shaken in an atmosphere of hydrogen at atmospheric pressure and laboratory temperature for several hours, during which time 5.04 liters of hydrogen were absorbed. The mixture was filtered, and the methanol removed in vacuo and the dark solid residue recrystallised from benzene to give 1,2-diamino-4-isopropoxycarbonylaminobenzene (10.4 g), m.p. 108°-110° C.

Aufarbeitung

  1. customwere absorbed
  2. filtrationThe mixture was filtered
  3. customthe methanol removed in vacuo
  4. customthe dark solid residue recrystallised from benzene

Quellen und Nachweise

ORD-Eintrag
ord-22ab45fac708435cae7f3fe6b69fef14
Quelldatensatz
uspto-grants-1977_09
Patentnummer
US04048326

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