HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diethyl Pyrocarbonate → 3-Amino-6-(trifluoromethyl)-1H-indazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diethyl Pyrocarbonate | HCID 3051 | — |
| Edukt | 3-Amino-6-trifluoromethylindazole-1-carboxylic acid ethyl ester | HCID 53694665 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 3-Amino-6-(trifluoromethyl)-1H-indazole | HCID 817909 | — |
Reaktionsschritte
Analogously to Example 22, 0.04 mol of 3-amino-6-trifluoromethylindazole and 50 ml of pyrocarbonic acid diethyl ester in 25 ml of ethanol give 3-amino-6-trifluoromethylindazole-1-carboxylic acid ethyl ester (melting point: 168°-169° C; 64% of theory) in 2 hours at 80° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04051252 |
| Quelldatensatz | uspto-grants-1977_09 |
| ORD ID | ord-45663ffc510940dfb989d3afcbed9a56 |
| Quellennotiz | uspto-grants-1977_09 |