Thionyl Chloride → 5-(4-Pentylphenyl)-pyrazin-2-yl 4-propylbenzoate

Beteiligte Stoffe

Reaktionsschritte

16.4 g of 4-propyl benzoic acid are boiled for hour with 24 g of SOCl2, which is followed by evaporating, dissolving the acid chloride obtained in 150 ml of toluene, adding 8 ml of pyridine and 24.2 g of 5-(4-pentylphenyl)-2-pyrazinol (obtainable analogously to Japanese Preliminary Published Application 144,770/84) and boiling for 2 hours. Cooling down and customary working up gives 5-(4-pentylphenyl)-pyrazin-2-yl 4-propylbenzoate.

Herkunft & Nachweise