4-Chlorobenzylamine → 5-[[(4-Chlorophenyl)methyl]amino]-8-[3-(trifluoromethyl)phenyl]-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one

HRID 2073202

Reaktionsgleichung

Reaktionsgleichung von HRID 2073202
CS[C:3]1[N:13]2[C:14]3[N:9]([C:10]([C:15]4[CH:20]=[CH:19][CH:18]=[C:17]([C:21]([F:24])([F:23])[F:22])[CH:16]=4)=[CH:11][CH2:12]2)[N:8]=[CH:7][C:6]=3[C:5](=[O:25])[N:4]=1.[Cl:26][C:27]1[CH:34]=[CH:33][C:30]([CH2:31][NH2:32])=[CH:29][CH:28]=1>>[Cl:26][C:27]1[CH:34]=[CH:33][C:30]([CH2:31][NH:32][C:3]2[N:13]3[C:14]4[N:9]([C:10]([C:15]5[CH:20]=[CH:19][CH:18]=[C:17]([C:21]([F:22])([F:23])[F:24])[CH:16]=5)=[CH:11][CH2:12]3)[N:8]=[CH:7][C:6]=4[C:5](=[O:25])[N:4]=2)=[CH:29][CH:28]=1

Komponenten

3

Edukt 2

HCID 660364-ChlorobenzylamineHCID 98853995-(Methylthio)-8-(3-(trifluoromethyl)phenyl)-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one

Produkt 1

HCID 157028085-[[(4-Chlorophenyl)methyl]amino]-8-[3-(trifluoromethyl)phenyl]-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one

Versuchsvorschrift

A 400 mg amount of 5-(methylthio)-8-[3-(trifluoromethyl)phenyl]-3H,6H-1,4,5a,8a-tetraazaacena-phthylen-3-one (prepared as described in Example 9) in 25.0 mg of 4-chlorobenzylamine was heated at 70° C. for 36 hours. The precipitate which formed was collected by filtration to give the product of the example as a white solid, m.p. 281°-282° C.

Aufarbeitung

  1. customThe precipitate which formed
  2. filtrationwas collected by filtration
  3. customto give the product of the example as a white solid, m.p. 281°-282° C.

Quellen und Nachweise

ORD-Eintrag
ord-4f27c47fcb914844ab8c2cf158f85472
Quelldatensatz
uspto-grants-1990_04
Patentnummer
US04916137

Verknüpfte Notizen

Wird geladen…