Propylamine → 2-aminooxy-N-propyl-acetamide

Reaktionsgleichung

C[O:2][C:3](=O)[CH2:4][O:5][N:6]1C(=O)C2C(=CC=CC=2)C1=O.[CH2:18]([NH2:21])[CH2:19][CH3:20]>>[NH2:6][O:5][CH2:4][C:3]([NH:21][CH2:18][CH2:19][CH3:20])=[O:2]

Komponenten

Edukt 2

HCID 7852Propylamine

HCID 748410Methyl ((1,3-dioxo-1,3-dihydro-2H-isoindol-2-YL)oxy)acetate

Produkt 1

HCID 553004112-aminooxy-N-propyl-acetamide

Versuchsvorschrift

Using (1,3-dioxo-1,3-dihydro-isoindol-2-yloxy)-acetic acid methyl ester obtained in Step A of Example 19 and n-propylamine as an amine, synthesis was performed according to the procedure described in Step A of Example 20 to give 2-aminooxy-N-propyl-acetamide.

Quellen und Nachweise

ORD-Eintrag: ord-2d3dd2ab90bd46b6bc9afad045133efc
Quelldatensatz: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07745663B2

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