2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid monomethyl ester → Nicardipine

Reaktionsgleichung

[CH3:1][C:2]1[NH:3][C:4]([CH3:25])=[C:5]([C:22]([OH:24])=[O:23])[CH:6]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([N+:19]([O-:21])=[O:20])[CH:14]=2)[C:7]=1S(OC)(=O)=O.CC1NC(C)=C(C(O)=O)C([C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][C:37]=2[C:42](F)(F)F)C=1[N+]([O-])=O.C[C:51]1[NH:52][C:53]([CH3:72])=C(C(O)=O)C(C2C3NOOC=3C=CC=2)C=1[N+]([O-])=O.CC1NC(C)=C(C(O)=O)C(C2C=CC=CC=2C(F)(F)F)C=1C#N.CC1NC(C)=C(C(O)=O)C(C2C=CC=C([N+]([O-])=O)C=2)C=1[C:103]([O:105][CH3:106])=[O:104]>C(O)(C)C.C(O)C.CO>[CH3:1][C:2]1[NH:3][C:4]([CH3:25])=[C:5]([C:22]([O:24][CH2:72][CH2:53][N:52]([CH2:42][C:37]2[CH:36]=[CH:41][CH:40]=[CH:39][CH:38]=2)[CH3:51])=[O:23])[CH:6]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([N+:19]([O-:21])=[O:20])[CH:14]=2)[C:7]=1[C:103]([O:105][CH3:106])=[O:104]