Triphenylphosphine → (3-Cyanobenzyl)triphenylphosphonium bromide

HRID 2074237Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2074237
[C:1]1([P:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:20]([C:22]1[CH:23]=[C:24]([CH:27]=[CH:28][CH:29]=1)[CH2:25][Br:26])#[N:21]>>[Br-:26].[C:20]([C:22]1[CH:23]=[C:24]([CH:27]=[CH:28][CH:29]=1)[CH2:25][P+:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)#[N:21]

Komponenten

3

Edukt 2

HCID 11776TriphenylphosphineHCID 97249Benzonitrile, 3-(bromomethyl)-

Produkt 1

HCID 2778355(3-Cyanobenzyl)triphenylphosphonium bromideAusbeute 72,7 %

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

Triphenylphosphine (2.8 g) was added to a Tol (50 ml) solution of 3-cyanobenzyl bromide (2.0 g), followed by stirring at 80° C. for 5 hours. This was cooled to room temperature, and the precipitated solid was collected by filtration, and washed with Tol. This was dried under reduced pressure to obtain (3-cyanobenzyl)(triphenyl)phosphonium bromide (3.4 g).

Aufarbeitung

  1. temperatureThis was cooled to room temperature
  2. filtrationthe precipitated solid was collected by filtration
  3. washwashed with Tol
  4. customThis was dried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-36f73407f0c34891ad33753396756501
Quelldatensatz
uspto-grants-2011_04
Patentnummer
US07919494B2

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