Propylamine → HCID 57869854, Verbindung

HRID 20744Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 20744
CO[C:3](=[O:13])[CH2:4][CH2:5][O:6][N:7]=[C:8]([O:10][CH2:11][CH3:12])[CH3:9].[CH2:14]([NH2:17])[CH2:15][CH3:16]>CO>[CH2:11]([O:10][C:8](=[N:7][O:6][CH2:5][CH2:4][C:3](=[O:13])[NH:17][CH2:14][CH2:15][CH3:16])[CH3:9])[CH3:12]

Komponenten

4

Edukt 2

HCID 7852PropylamineHCID 71331645Methyl 3-{[(1-ethoxyethylidene)amino]oxy}propanoate

Produkt 1

HCID 57869854HCID 57869854, VerbindungAusbeute 86 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Reaktionsbedingungen

Temperatur
55 °C

Versuchsvorschrift

To a known compound, 3-(1-ethoxy-ethylideneaminooxy)-propanoic acid methyl ester (CAS No. 97164-30-2, 300 mg, 1.585 mmol) were added methanol (3 ml) and n-propylamine (1.3 ml), and the mixture was stirred at 55° C. for 15 hours. The reaction mixture was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography to give N-(2-propylcarbamoyl-ethoxy)-acetimidic acid ethyl ester (296 mg, 86% yield).

Aufarbeitung

  1. concentrationThe reaction mixture was concentrated under reduced pressure
  2. customthe residue was purified by silica gel column chromatography

Quellen und Nachweise

ORD-Eintrag
ord-cdbdab0d045348dd836917e4c0d1343b
Quelldatensatz
uspto-grants-2010_06
Patentnummer
US07745663B2

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