4-Amino-5-pyrimidinecarboxamide → HCID 135923523, Verbindung

Beteiligte Stoffe

Reaktionsschritte

In analogy to example 3.3, 4-amino-5-pyrimidinecarboxamide and (2-m-tolyl-ethoxy)-acetic acid methyl ester (prepared from 2-m-tolyl-ethanol [1875-89-4] in analogy to example 3.1-3.2) reacted in the presence of LiHMDS in THF to yield the title compound (after purification of the crude product with column chromatography (silica gel, EtOAc/MeOH) and crystallization from TBME) as white solid. MS: m/e=295.5 [M−H−].

Herkunft & Nachweise