HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methylamine → 5-Bromo-N-methyl-3-nitropyridin-2-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methylamine | HCID 6329 | — |
| Edukt | Tetrahydrofuran | HCID 8028 | — |
| Edukt | 5-Bromo-2-chloro-3-nitropyridine | HCID 7019412 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 5-Bromo-N-methyl-3-nitropyridin-2-amine | HCID 10868149 | — |
Reaktionsschritte
5-bromo-2-chloro-3-nitropyridine (456 mg, 1920 μmol) was dissolved in MeOH (6.0 ml) and methylamine, 2.0 M solution in tetrahydrofuran (2.5 ml, 5.0 mmol) was added. The reaction was stirred at room temperature for 6 hours, allowed to stand at room temperature overnight, and then concentrated. material was taken directly to the next step.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07928140B2 |
| Quelldatensatz | uspto-grants-2011_04 |
| ORD ID | ord-477fb39ca8fe4324914ee8e5e98c1828 |
| Quellennotiz | uspto-grants-2011_04 |