Isoamyl Nitrite → 2-Hydroxy-4-nitrobenzene diazonium triflate

HRID 2081927Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2081927
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][C:3]=1[OH:11].[F:12][C:13]([F:19])([F:18])[S:14]([OH:17])(=[O:16])=[O:15].[N:20](OCCC(C)C)=O>CO>[O-:17][S:14]([C:13]([F:19])([F:18])[F:12])(=[O:16])=[O:15].[OH:11][C:3]1[CH:4]=[C:5]([N+:8]([O-:10])=[O:9])[CH:6]=[CH:7][C:2]=1[N+:1]#[N:20]

Komponenten

5

Edukt 3

HCID 8053Isoamyl NitriteHCID 62406Trifluoromethanesulfonic acidHCID 49847212-Amino-5-Nitrophenol

Produkt 1

HCID 867449522-Hydroxy-4-nitrobenzene diazonium triflate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

To an ice cooled solution containing 5 parts of 2-amino-5-nitrophenol and 9.6 parts of trifluoromethane sulfonic acid in 150 parts of methanol was slowly added 3.9 parts of isoamyl nitrite to complete diazotization. The solution was filtered and the filtrate was poured into 700 parts of ethyl ether. The precipitate was collected, washed with ether and dried under vacuum to give 4.5 parts of product with purity >95%.

Aufarbeitung

  1. filtrationThe solution was filtered
  2. additionthe filtrate was poured into 700 parts of ethyl ether
  3. customThe precipitate was collected
  4. washwashed with ether
  5. customdried under vacuum
  6. customto give 4.5 parts of product with purity >95%

Quellen und Nachweise

ORD-Eintrag
ord-79b644a726fa4c86914f330be39449f8
Quelldatensatz
uspto-grants-1993_02
Patentnummer
US05186865

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