Acetohydrazide → HCID 12207321, Verbindung

HRID 2082682Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2082682
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][C:3]=1[N:9]=[C:10]=[S:11].[C:12]([NH:15][NH2:16])(=[O:14])[CH3:13]>C1COCC1>[C:12]([NH:15][NH:16][C:10]([NH:9][C:3]1[CH:4]=[C:5]([CH3:8])[CH:6]=[CH:7][C:2]=1[Cl:1])=[S:11])(=[O:14])[CH3:13]

Komponenten

4

Edukt 2

HCID 14039AcetohydrazideHCID 227520811-Chloro-2-isothiocyanato-4-methylbenzene

Produkt 1

HCID 12207321HCID 12207321, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

One tenth mole, 18.3 g., of 2-chloro-5-methylphenylisothiocyanate and 11.0 g. (0.15 mole) of acetylhydrazine were refluxed for 7 hours in 500 ml. of THF. After cooling, the insoluble product was collected by filtration. The crude product was collected by filtration. The crude product was washed with water, filtered and dried. The yield was 25 g. of 1-acetyl-4-(2-chloro-5-methylphenyl)-3-thiosemicarbazide, m.p. about 145°-157° C.

Aufarbeitung

  1. temperatureAfter cooling
  2. filtrationthe insoluble product was collected by filtration
  3. filtrationThe crude product was collected by filtration
  4. washThe crude product was washed with water
  5. filtrationfiltered
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-e6e8bd6e24c4465d93b254380fbb8157
Quelldatensatz
uspto-grants-1978_04
Patentnummer
US04082762

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