Sodium Carbonate → Methyl s-phenyl-l-cysteinate

HRID 2085711Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2085711
C(OC([NH:8][C@H:9]([C:18]([O:20][CH3:21])=[O:19])[CH2:10][S:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=O)(C)(C)C.C([O-])([O-])=O.[Na+].[Na+]>O1CCOCC1>[C:12]1([S:11][CH2:10][C@@H:9]([C:18]([O:20][CH3:21])=[O:19])[NH2:8])[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Komponenten

4

Edukt 2

HCID 10340Sodium CarbonateHCID 18637399Methyl n-(tert-butoxycarbonyl)-s-phenylcysteinate

Produkt 1

HCID 54282006Methyl s-phenyl-l-cysteinate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

A mixture of Example 133A in 1:1 dioxane/4M HCl at room temperature was stirred for 3 hours, poured into saturated Na2CO3 (400 mL), and extracted with ethyl acetate (3×300 mL). The combined extracts were dried (Na2SO4), filtered, and concentrated to provide the desired product.

Aufarbeitung

  1. extractionextracted with ethyl acetate (3×300 mL)
  2. dry with materialThe combined extracts were dried (Na2SO4)
  3. filtrationfiltered
  4. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-877cea8b5e544be19581d2c6ac83962c
Quelldatensatz
uspto-grants-2004_04
Patentnummer
US06720338B2

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