Chloroacetyl chloride → 4-chloro-N'-(2-chloroacetyl)benzohydrazide

HRID 2086

Reaktionsgleichung

Reaktionsgleichung von HRID 2086
[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[CH:4][CH:3]=1.[Cl:12][CH2:13][C:14](Cl)=[O:15]>O1CCOCC1>[Cl:12][CH2:13][C:14]([NH:9][NH:8][C:6](=[O:7])[C:5]1[CH:10]=[CH:11][C:2]([Cl:1])=[CH:3][CH:4]=1)=[O:15]

Komponenten

4

Edukt 2

HCID 6577Chloroacetyl chlorideHCID 108164-Chlorobenzohydrazide

Produkt 1

HCID 5212924-chloro-N'-(2-chloroacetyl)benzohydrazide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

To a solution of p-chlorobenzoic hydrazide (11.2 g) in dioxane (100 ml) was added chIoroacetyl chloride (6 ml). The resulting mixture was refluxed for three hours, cooled to room temperature and filtered. The resulting solid was washed with ethyl ether and dried to yield N'-chloroacetyl-4-chlorobenzoic hydrazide as white solid.

Aufarbeitung

  1. temperatureThe resulting mixture was refluxed for three hours
  2. filtrationfiltered
  3. washThe resulting solid was washed with ethyl ether
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-20add643e25f4ff484bb9c80dc811185
Quelldatensatz
uspto-grants-1998_03
Patentnummer
US05728694

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