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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2089139Erstellt: 26. Oktober 2026

4-(tert-Butyldimethylsilyloxy)cyclohexanone → N-{1-[4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexyl]-azetidin-3-yl}-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide

https://huagongshe.com/reaction/2089139

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-(tert-Butyldimethylsilyloxy)cyclohexanoneHCID 10609430—
EduktN-Azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA saltHCID 86660176—
ProduktN-{1-[4-(tert-Butyl-dimethyl-silanyloxy)-cyclohexyl]-azetidin-3-yl}-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamideHCID 58548829—

Reaktionsschritte

The title compound was prepared as a white solid from reaction of (N-azetidin-3-yl-2-(5-trifluoromethyl-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt (as prepared in Example 1, Step D) and 4-(tert-butyl-dimethyl-silanyloxy)-cyclohexanone using the procedure described in Step E of Example 1.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08436023B2
Quelldatensatzuspto-grants-2013_05
ORD IDord-dd5ad6d98f844a1eb99a60ee5647a9ca
Quellennotizuspto-grants-2013_05