8-Amino-1-isobutyl-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one → 2-[5-Chloro-2-(1-isobutyl-5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino)-pyrimidin-4-ylamino]-3-fluoro-N-methyl-benzamide
Reaktionsgleichung
[Cl:20][c:21]1[n:22][cH:23][c:24]([Cl:39])[c:25]([NH:27][c:28]2[c:29]([C:30](=[O:31])[NH:32][CH3:33])[cH:34][cH:35][cH:36][c:37]2[F:38])[n:26]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[N:7]([CH2:15][CH:16]([CH3:17])[CH3:18])[C:8](=[O:14])[CH2:9][CH2:10][C:11]2([CH3:12])[CH3:13]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[N:7]([CH2:15][CH:16]([CH3:17])[CH3:18])[C:8](=[O:14])[CH2:9][CH2:10][C:11]2([CH3:12])[CH3:13])[c:21]1[n:22][cH:23][c:24]([Cl:39])[c:25]([NH:27][c:28]2[c:29]([C:30](=[O:31])[NH:32][CH3:33])[cH:34][cH:35][cH:36][c:37]2[F:38])[n:26]1Komponenten
3
Edukt 2
Produkt 1
Quellen und Nachweise
- ORD-Eintrag
- ord-bf547547c9da4e64bfe73ac64b443264
- Quelldatensatz
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)