(4E)-N-Methoxy-6-methyl-3,4-dihydro-2H-1-benzopyran-4-imine → 6-Chloro-7-methyl-3,4-dihydro-2H-1-benzopyran-4-amine

HRID 2092161Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2092161
CO[N:3]=[C:4]1[C:13]2[C:8](=[CH:9][C:10]([CH3:15])=[C:11]([Cl:14])[CH:12]=2)[O:7][CH2:6][CH2:5]1.CON=C1C2C(=CC=C(C)C=2)OCC1>>[Cl:14][C:11]1[CH:12]=[C:13]2[C:8](=[CH:9][C:10]=1[CH3:15])[O:7][CH2:6][CH2:5][CH:4]2[NH2:3]

Komponenten

3

Edukt 2

HCID 86605441(4E)-N-Methoxy-6-methyl-3,4-dihydro-2H-1-benzopyran-4-imineHCID 866054426-Chloro-7-methylchroman-4-one O-methyl oxime

Produkt 1

HCID 166430296-Chloro-7-methyl-3,4-dihydro-2H-1-benzopyran-4-amine

Versuchsvorschrift

The title compound was prepared using the procedure as described in Example 7B, substituting the product of Example 13A for the product of Example 7A. 1H NMR (300 MHz, CDCl3) δ 7.27 (s, 1H), 6.68 (s, 1H), 4.15-4.29 (m, 2H), 3.98 (m, 1H), 2.29 (s, 3H), 2.07-2.17 (m, 1H), 1.75-1.85 (m, 1H). MS (DCI) m/e 198 (M+H)+.

Quellen und Nachweise

ORD-Eintrag
ord-574dfd4cd4ae4ec1a803ecf98ba1633d
Quelldatensatz
uspto-grants-2013_05
Patentnummer
US08440691B2

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