4-Hydroxy-1-(2-methoxy-ethyl)-cyclohexanecarboxylic acid ethyl ester → HCID 58230072, Verbindung
Reaktionsgleichung
C(O[C:4]([C:6]1([CH2:13][CH2:14]OC)[CH2:11][CH2:10][CH:9]([OH:12])[CH2:8][CH2:7]1)=[O:5])C.[NH2:17][C:18]1[CH:23]=[CH:22][C:21]([O:24][S:25]([CH:28]2[CH2:30][CH2:29]2)(=[O:27])=[O:26])=[CH:20][CH:19]=1>>[OH:12][CH:9]1[CH2:8][CH2:7][C:6]2([C:4](=[O:5])[N:17]([C:18]3[CH:23]=[CH:22][C:21]([O:24][S:25]([CH:28]4[CH2:30][CH2:29]4)(=[O:27])=[O:26])=[CH:20][CH:19]=3)[CH2:14][CH2:13]2)[CH2:11][CH2:10]1Komponenten
3
Versuchsvorschrift
The title compound was prepared in analogy to example 108, step 3 from 4-hydroxy-1-(2-methoxy-ethyl)-cyclohexanecarboxylic acid ethyl ester (obtained in example 2, step 3) by treatment with cyclopropanesulfonic acid 4-amino-phenyl ester as a mixture of cis and trans diastereomers. MS (m/e): 366.137 [MH+].
Quellen und Nachweise
- ORD-Eintrag
- ord-72e17dba5aee46c8a8dbad433cf65782
- Quelldatensatz
- uspto-grants-2013_05