2-Isopropylthiazole → 8-(2-Isopropyl-1,3-thiazol-5-yl)-1,4-dioxaspiro[4.5]decan-8-ol
Reaktionsgleichung
[CH:1]([C:4]1[S:5][CH:6]=[CH:7][N:8]=1)([CH3:3])[CH3:2].[O:9]1[C:13]2([CH2:18][CH2:17][C:16](=[O:19])[CH2:15][CH2:14]2)[O:12][CH2:11][CH2:10]1>>[CH:1]([C:4]1[S:5][C:6]([C:16]2([OH:19])[CH2:17][CH2:18][C:13]3([O:12][CH2:11][CH2:10][O:9]3)[CH2:14][CH2:15]2)=[CH:7][N:8]=1)([CH3:3])[CH3:2]Komponenten
3
Versuchsvorschrift
The title compound was prepared as a white solid from 2-iso-propyl-thiazole and 1,4-dioxa-spiro[4.5]decan-8-one using the procedure described in Step A of Example 33.
Quellen und Nachweise
- ORD-Eintrag
- ord-d9c8072f92ac49019b51dcdc3ea0a08c
- Quelldatensatz
- uspto-grants-2013_05
- Patentnummer
- US08450304B2
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