HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(Trifluoromethyl)phenylboronic acid → [6-methoxy-1-(4-trifluoromethyl-phenyl)-isoquinolin-3-yl]-(1H-pyrazol-3-yl)-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| Edukt | HCID 178487533 | HCID 178487533 | — |
| Produkt | [6-methoxy-1-(4-trifluoromethyl-phenyl)-isoquinolin-3-yl]-(1H-pyrazol-3-yl)-amine | HCID 178487352 | — |
Reaktionsschritte
Similar procedure as described in example 131 was used, starting from (1-chloro-6-methoxy-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and 4-trifluoromethyl-phenylboronic acid to give [6-methoxy-1-(4-trifluoromethyl-phenyl)-isoquinolin-3-yl]-(1H-pyrazol-3-yl)-amine. LC-MS m/e 385(MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07572809B2 |
| Quelldatensatz | uspto-grants-2009_08 |
| ORD ID | ord-e908632edf6c4fb78ea4f0d493645e43 |
| Quellennotiz | uspto-grants-2009_08 |