HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(3,5-Difluorophenyl)boronic acid → [1-(3,5-difluoro-phenyl)-6-methoxy-isoquinolin-3-yl]-(1H-pyrazol-3-yl)-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (3,5-Difluorophenyl)boronic acid | HCID 2734338 | — |
| Edukt | HCID 178487533 | HCID 178487533 | — |
| Produkt | [1-(3,5-difluoro-phenyl)-6-methoxy-isoquinolin-3-yl]-(1H-pyrazol-3-yl)-amine | HCID 178487366 | — |
Reaktionsschritte
Similar procedure as described in example 131 was used, starting from (1-chloro-6-methoxy-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and 3,5-difluoro-phenylboronic acid to give [1-(3,5-difluoro-phenyl)-6-methoxy-isoquinolin-3-yl]-(1H-pyrazol-3-yl)-amine. LC-MS m/e 353(MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07572809B2 |
| Quelldatensatz | uspto-grants-2009_08 |
| ORD ID | ord-44dc3e6bffdc4a068c91ea3f26b54bbb |
| Quellennotiz | uspto-grants-2009_08 |