1,8-Diiodooctane → 5-(8-(3H-1,2,3-triazol-4-ylthio)octylthio)-1H-1,2,3-triazole

HRID 2103942Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2103942
[SH:1][C:2]1[NH:6][N:5]=[N:4][CH:3]=1.I[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]I>C(O)C>[N:4]1[CH:3]=[C:2]([S:1][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][S:1][C:2]2[NH:6][N:5]=[N:4][CH:3]=2)[NH:6][N:5]=1

Komponenten

4

Edukt 2

HCID 906051,8-DiiodooctaneHCID 178527741HCID 178527741, Verbindung2×

Produkt 1

HCID 1784209285-(8-(3H-1,2,3-triazol-4-ylthio)octylthio)-1H-1,2,3-triazoleAusbeute 42 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

20 mmole of 5-mercapto-1H-1,2,3-triazole (sodium salt) was dissolved in 20 ml of ethanol in stirring. 10 mmole of 1,8-diiodooctane was added dropwise to the solution of 5-mercapto-1H-1,2,3-triazole (sodium salt), and stirred overnight. After the solvent was evaporated in vacuum, the residual was washed with 50 ml pure H2O for three times, and then with 50 ml hexane for 3 times. At last, the residual was dried in oven at 60° C. for 24 hours. 1.30 g product was obtained as white solid. Yield: 42%. 1H NMR (DMSO): δ (ppm) 7.88 (2H, s), 2.86 (4H, t, JH-H=7.14), 1.50 (4H, m), and 1.20-1.31 (8H, m).

Aufarbeitung

  1. stirringstirred overnight
  2. customAfter the solvent was evaporated in vacuum
  3. washthe residual was washed with 50 ml pure H2O for three times
  4. customAt last, the residual was dried in oven at 60° C. for 24 hours

Quellen und Nachweise

ORD-Eintrag
ord-2fee72b930914d4face73da053944f0d
Quelldatensatz
uspto-grants-2009_08
Patentnummer
US07576165B2

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