2,3,4-Tri-o-benzoyl-l-rhamnono-1,5-lactone → Wrypvzdhvrcrog-xjksgupxsa-

HRID 2104225Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2104225
[C:1]([O:9][C@@H:10]1[C@H:16](OC(=O)C2C=CC=CC=2)[C@@H:15]([O:26][C:27](=[O:34])[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C@H:14]([CH3:35])[O:13][C:11]1=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CCN(CC)CC.C(Cl)(Cl)Cl>[C:1]([O:9][C:10]1[C:11]([O:13][C@@H:14]([CH3:35])[C@H:15]([O:26][C:27](=[O:34])[C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH:16]=1)=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

3

Edukt 1

HCID 112368422,3,4-Tri-o-benzoyl-l-rhamnono-1,5-lactone

Produkt 1

HCID 11221893Wrypvzdhvrcrog-xjksgupxsa-Ausbeute 65 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 18929042Triethylamine chloroformLösungsmittel

Versuchsvorschrift

The compound (VII) (13.2 g, 27.8 mmol) is dissolved in Et3N:CHCl3 (1:4, 500 ml) under N2 current and stirred for 16 hours at a room temperature. After the reaction is finished, it is washed by water. An organic layer is dried using anhydrous MgSO4. The solution is vacuum concentrated and then the compound (VIII) (6.37 g, 65%) is isolated using flash column chromatography (toluene/EtOAc, 10:1, v/v).

Aufarbeitung

  1. washit is washed by water
  2. customAn organic layer is dried
  3. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-44de9b80a9324e41ac6621254c1a76c5
Quelldatensatz
uspto-grants-2009_08
Patentnummer
US07576225B2

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