5-Methyl-2-furanmethanethiol → 4-[[(1R)-2-Hydroxy-1-methylethyl]amino]-2-[[(5-methyl-2-furanyl)methyl]thio]-7(8H)-pteridinone
Reaktionsgleichung
F[C:2]1[C:7](F)=[CH:6][CH:5]=C[C:3]=1[CH2:9][S:10]([C:13]1[N:22]=[C:21]([NH:23][C@H:24]([CH3:27])[CH2:25][OH:26])[C:20]2[N:19]=[CH:18][C:17](=[O:28])[NH:16][C:15]=2[N:14]=1)(=O)=O.CC1[O:34]C(CS)=CC=1>>[OH:26][CH2:25][C@H:24]([NH:23][C:21]1[C:20]2[N:19]=[CH:18][C:17](=[O:28])[NH:16][C:15]=2[N:14]=[C:13]([S:10][CH2:9][C:3]2[O:34][C:6]([CH3:5])=[CH:7][CH:2]=2)[N:22]=1)[CH3:27]Komponenten
3
Versuchsvorschrift
The titled compound (0.058 g) was prepared by the method of Example 13, step (c) using the product from Example 13, step (a) (0.20 g) and 5-methyl-2-furanylmethylmercaptan (0.15 g of 80% pure).
Quellen und Nachweise
- ORD-Eintrag