Dabco → 1-(4-{4-[3-[3-(4-Fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]-phenoxymethyl}-benzyl)-4-aza-1-azoniabicyclo[2.2.2]octane bromide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Dabco	HCID 9237	—
Edukt	1-[4-(4-Bromomethylbenzyloxy)-phenyl]-3-[3-(4-fluorophenyl)-3-hydroxypropyl]4-(4-methoxyphenyl)-azetidin-2-one	HCID 21083167	—
Lösungsmittel	Toluene	HCID 1140	—
Produkt	1-(4-{4-[3-[3-(4-Fluorophenyl)-3-hydroxypropyl]-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]-phenoxymethyl}-benzyl)-4-aza-1-azoniabicyclo[2.2.2]octane bromide	HCID 21083163	—

Reaktionsschritte

Compound (25) and DABCO were dissolved in toluene and reacted analogously to Example IV, giving the product (26) as a colorless solid of molecular weight 716.70 (C39H43BrFN3O4); MS (ESI): 636.3 (MH+).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07579339B2
Quelldatensatz	uspto-grants-2009_08
ORD ID	ord-a0c4a659c15a4886a2686d4f6966de97
Quellennotiz	uspto-grants-2009_08