Methyl acetoacetate → HCID 86594074, Verbindung
Reaktionsgleichung
[CH3:1][O:2][C:3](=[O:8])[CH2:4][C:5](=O)[CH3:6].[F:9][C:10]([F:27])([F:26])[C:11]1[CH:12]=[C:13]([C:21](=O)[CH:22](Br)[CH3:23])[CH:14]=[C:15]([C:17]([F:20])([F:19])[F:18])[CH:16]=1.[CH:28]1([CH2:34][NH2:35])[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>>[CH3:1][O:2][C:3]([C:4]1[C:22]([CH3:23])=[C:21]([C:13]2[CH:12]=[C:11]([C:10]([F:27])([F:26])[F:9])[CH:16]=[C:15]([C:17]([F:20])([F:19])[F:18])[CH:14]=2)[N:35]([CH2:34][CH:28]2[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]2)[C:5]=1[CH3:6])=[O:8]Komponenten
4
Versuchsvorschrift
The title compound was prepared according to example 68, using 3-oxo-butyric acid methyl ester as compound of formula R, 1-(3,5-bis-trifluoromethyl-phenyl)-2-bromo-propan-1-one as compound of formula S and cyclohexanemethylamine, as R3—(CH2)m—NH2, MS (EI) 461.2 (M)+.
Quellen und Nachweise
- ORD-Eintrag
- ord-9b2ea821dff4491fbdf37713df51248d