Chloroacetyl chloride → N-(2-cyano-ethyl)-N-methyl-2-piperazin-1-yl-acetamide

HRID 2105861

Reaktionsgleichung

Reaktionsgleichung von HRID 2105861
C(O[C:6]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=O)(C)(C)C.ClC[C:16](Cl)=[O:17].[C:19]([CH2:21][CH2:22][NH:23][CH3:24])#[N:20]>>[C:19]([CH2:21][CH2:22][N:23]([CH3:24])[C:16](=[O:17])[CH2:6][N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1)#[N:20]

Komponenten

4

Edukt 3

HCID 6577Chloroacetyl chlorideHCID 69656Propanenitrile, 3-(methylamino)-HCID 143452tert-Butyl piperazine-1-carboxylate

Produkt 1

HCID 28881147N-(2-cyano-ethyl)-N-methyl-2-piperazin-1-yl-acetamide

Versuchsvorschrift

The title compound was prepared from 1-tert-butyloxycarbonyl-piperazine, chloroacetylchloride and N-(2-cyanoethyl)-N-methylamine in an analogous manner as described in example 21.

Quellen und Nachweise

ORD-Eintrag
ord-8d917019956b43dd908011bb551c8953
Quelldatensatz
uspto-grants-2009_08
Patentnummer
US07579368B2

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